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Start your patients on OTEZLA today

OTEZLA offers convenient, oral dosing1


Treatment begins with a 5-day titration1:

otezla dosing

After the titration period, the maintenance dose of OTEZLA is 30 mg twice daily for most patients1

  • This titration is intended to reduce gastrointestinal symptoms associated with initial therapy
  • OTEZLA can be taken with or without food
  • Patients should not split, crush, or chew the tablet

The dose of OTEZLA should be reduced to 30 mg once daily in patients with severe renal impairment1*

  • For initial dosage titration, it is recommended that OTEZLA be titrated using only the AM schedule shown above

Creatinine clearance (CrCl) <30 mL/min estimated by the Cockcroft–Gault equation.

Reference: 1. OTEZLA Summary of Product Characteristics. Stockley Park, Uxbridge, UK: Celgene Europe, Ltd; 2016.

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