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The OTEZLA® international website
This site is intended for healthcare professionals outside the U.S.
aPALACE 1-3 pooled analysis. Data as observed; includes all patients who received OTEZLA 30 mg BID, regardless of whether they were initially randomized to OTEZLA 30 mg BID or placebo patients who were re-randomized to OTEZLA at week 16 or week 24.
Patients treated with OTEZLA 30 mg BID achieved
significantly greater improvement vs placebo in MASES (enthesitis)
score (mean change of -1.3 vs 0.9, P<0.05) at week 242†
*Pooled patient data from PALACE 1-3; includes all randomized patients with preexisting enthesopathy (baseline MASES score >0; n = 945). Resolution was defined as a MASES score of 0.
†LOCF; for patients who qualified for early escape at week 16, the week 16 value was carried forward.
BID, twice daily; LOCF, last observation carried forward; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; PALACE, Psoriatic Arthritis Long-Term Assessment of Clinical Efficacy.
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