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The OTEZLA® international website

This site is intended for healthcare professionals outside the U.S.

OTEZLA DELIVERS PROVEN AND SUSTAINED EFFICACY1

Sustained PASI response up to 32 weeks1,a

aESTEEM 1 study; full analysis set, data as observed.

OTEZLA sustains improvement in skin severity

See the OTEZLA difference

Real patients, real pictures.*

Baseline

Week 16 PASI-45 result

Individual results may vary.

Week 32 PASI-68 result

Individual results may vary.

*Photos taken from the ESTEEM clinical trial program, which evaluated OTEZLA 30 mg BID in patients with active plaque psoriasis.

BID, twice daily; ESTEEM, Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis; PASI, Psoriasis Area and Severity Index.

OTEZLA DELIVERS RAPID AND SUSTAINED EFFICACY IN BIOLOGIC-NAÏVE PATIENTS2,3†

Sustained PASI improvement up to 2 years2,3,a

aLIBERATE study. Data as observed among patients with a value at the time point indicated, with no imputation for missing values.

OTEZLA improves skin clearance in biologic-naïve
patients, with response maintained up to 2 years2,3

References:

  1. Papp K, Reich K, Leonardi CL, et al. Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1). J Am Acad Dermatol. 2015;73:37-49.
  2. Data on file, Celgene Corporation.
  3. Reich K, Gooderham M, Bewley A, et al. Safety and efficacy of apremilast through 104 weeks in patients with moderate to severe psoriasis who continued on apremilast or switched from etanercept treatment: findings from the LIBERATE study. J Eur Acad Dermatol Venereol. doi:10.1111/jdv.14738.
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